Why is participation important?

Every woman’s experience with uterine fibroids is different. Through responses to survey questions, COMPARE-UF collects information from women volunteers to help understand patterns of symptom relief and the ability to get pregnant. Ultimately, COMPARE-UF hopes to help patients and their clinicians make informed decisions about treatment.

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Information Collected
by the Registry

COMPARE-UF will follow 10,000 women from nine medical centers in the U.S. for about three years as they make decisions about treatment for their fibroids. Participants are women between the ages of 18 and 54 who have been diagnosed with uterine fibroids and who are not in the transition to menopause.

Sharing Results

Find out about what we are learning from women diagnosed with uterine fibroids. Check back here for results.



Summary of Study Results

In this COMPARE-UF fibroid study, researchers compared the 2 most common surgical treatments for women with fibroid symptoms—hysterectomy and myomectomy—to see which was more effective. Researchers also looked at each procedure by surgical approach—abdominal, vaginal, or other, less invasive, methods.

As many as 3 out of 4 women have fibroids,

but not all women have symptoms or require treatment.

For women who require treatment,
there are alternatives to hysterectomy.